ABSTRACT
Parkinson disease(PD)is the second most common neurodegenerative disease,and its motor and non-motor symptoms seriously affect the patients' quality of life.The existing methods of evaluation of PD contain a lot of shortages,such as inter-rater variability and recall bias,which promote patients,clinicians and researchers to have a strong demand for more objective and long-term assessment and monitoring methods.The wearable device-based quantitative technology,which is easy to operate and have the features of objective quantification,daily permanence and meticulous accuracy,makes it have an extensive series of perspective and advantage for application in the management of PD.This article describes,and illustrates with several examples,the applications of wearable devices in the diagnosis and treatment of various motor symptoms such as bradykinesia,resting tremor,gait disorder,motor fluctuation,dyskinesia and non-motor symptoms.We also discuss its current limitations and future directions.